FTY720 Hydrochloride(CAS:162359-56-0)(分子式:C19H34ClNO2)-生物分子-试剂-生物在线
上海甄准生物科技有限公司
FTY720 Hydrochloride(CAS:162359-56-0)(分子式:C19H34ClNO2)

FTY720 Hydrochloride(CAS:162359-56-0)(分子式:C19H34ClNO2)

商家询价

产品名称: FTY720 Hydrochloride(CAS:162359-56-0)(分子式:C19H34ClNO2)

英文名称: FTY720 Hydrochloride

产品编号: TRC-F805000

产品价格: 0

产品产地: CANADA

品牌商标: TRC

更新时间: null

使用范围: null

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1) Cat. No.: TRC-F805000; 2) Chemical Name: FTY720 Hydrochloride; 3) CAS No.: 162359-56-0; 4) Mol. Formula: C19H34ClNO2; 5) Mol. Weight: 343.93; 6) Packing Size: 5mg / 50mg; 7) Appearence: White Solid; 8) Application Notes: FTY720  is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720  is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720  us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).; 9) Synonym: 2-Amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol Hydrochloride; Fingolimod Hydrochloride;; 10) Solubility: DMSO, Ethanol, Methanol; 11) Storage condition: -20°C Freezer; 12) References: Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),